Liangcheng Du
Professor Chemistry University of Nebraska-Lincoln
Contact
- Address
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HAH 729
Lincoln NE 68588-0304 - Phone
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402-472-2998 On-campus 2-2998
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ldu3@unl.edu
Research interests
Novel antibiotics and other bioactive agents from microorganisms often can be produced or synthesized in large quantities at an affordable cost, so the study of underlying biosynthetic pathways for these complex, small molecule structures has the potential to advance both basic and applied research. Dr. Du's laboratory has identified small molecule products from the gliding bacteria Lysobacter species and fungal endophytes that have antibiotic, anticancer, and antifungal properties. Students in Dr. Du's laboratory are working to understand and exploit the redox-sensing biosynthetic pathways for these products so they can be engineered to function with high yields in controlled expression systems, and as paradigms for orthologous oxidative stress sensing pathways in more complex organisms.