Edward Harris
Professor Biochemistry University of Nebraska-Lincoln
Contact
- Address
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BEAD N133
Lincoln NE 68588-0664 - Phone
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402-472-7468 On-campus 2-7468
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eharris5@unl.edu
Research interests
The liver is an absorptive organ with a highly specialized reticulated endothelium rich in a variety of cell surface scavenger receptors that clear circulating proteins, lipids, and other macromolecules. Dr. Harris has extensively characterized the stabilin class of receptors, due to its rapid and continuous endocytic clearance activity and strong affinity for heparin, heparin-like molecules, hyaluronan and other circulating glycosaminoglycans, as well as low-density lipoproteins and related ligands. Dr. Harris' laboratory has shown that stabilins have a critical role in heparin clearance, which has a strong biomedical impact because of the widespread use of heparin in many complex surgical procedures. Although a relatively new investigator, Dr. Harris has established strong collaborations to characterize the role of stabilins in clearing clinically relevant synthetic heparins.
Education
- BS, Brigham Young University, 1996
- Ph D, Louisiana State University Health Sciences Center, 2001