The Molecular Mechanism of Disease Training Program was initiated through institutional funding from the University of Nebraska-Lincoln prior to being funded by NIGMS grants T32GM107001 (2015-2020) and T32GM136593 (2020-2025). Outcomes for the total cohort of trainees supported by NIH funding since the MMoD program began are provided.

Understanding how normal processes in the cell operate incorrectly at the molecular level during disease initiation and progression is vital to develop strategies to control disease. Interdisciplinary research that integrates methodologies across traditional fields is needed to advance the definition of molecular processes. The proposed predoctoral program in Molecular Mechanisms of Disease at the University of Nebraska- Lincoln will use collaborative research projects, student-centered teaching, and diverse career development opportunities to develop a workforce of team-oriented scientists with critical expertise in the interdisciplinary study of disease progression.

NIH MMoD Training Cohort: 39 students 
(2015-2025)

PhD Recipients: 18
Average time to PhD degree: 5.2 years
MS Degree Recipients: 4
Total number of publications of graduates: 62 (3.4 papers per trainee)

Career Paths of Alumni

Postdoctoral Fellow, Miyazaki University
Postdoctoral Fellow, Rutgers University
Postdoctoral Fellow, University of North Carolina-Chapel Hill
Postdoctoral Fellow, University of Michigan
Postdoctoral Fellow, University of Colorado Anschutz Medical Campus
Postdoctoral Fellow, Rice University 
Manager, Biologics Mass Spectrometry
Extension Assistant Professor, University of Nebraska-Lincoln
Director of Research, National Multiple Sclerosis Society
Senior Research Scientist, Charles River Laboratories
Scientist, 23andMe
Study Director, Neuralink
Analytical Research Scientist, National Council for Air and Stream Improvement
Senior Research Analyst, Pearson
Embryologist, Heartland Center for Reproductive Medicine

 

Recent Publications of Trainees

WhiB-like proteins: Diversity of structure, function and mechanism.
Biochimica et biophysica acta. Molecular cell research2024 Oct; 1871 (7) 119787Guiza Beltran, Daisy; Wan, Tao; Zhang, LiMei2024
Traumatic brain injury heterogeneity affects cell death and autophagy.
Experimental brain research2024 Jul; 242 (7) 1645-1658McDonald, Brandon Z; Tarudji, Aria W; Zhang, Haipeng; Ryu, Sangjin; Eskridge, Kent M; Kievit, Forrest M2024
Engineering a multicompartment in vitro model for dorsal root ganglia phenotypic assessment.
Journal of biomedical materials research. Part B, Applied biomaterials2023 Nov; 111 (11) 1903-1920Caparaso, Sydney M; Redwine, Adan L; Wachs, Rebecca A2023

Trends 

https://report.nih.gov/nihdatabook/report/267/